SUMITOMO HEAVY INDUSTRIES TECHNICAL REVIEW
Development of Cassette Type FDG Synthesizer (F200)
Eiji TANAKA

Development of Cassette Type FDG Synthesizer (F200)

In late years, the PET examination by FDG begins to spread widely even into general hospitals. We have delivered PET medicine production systems, to more than 80 facilities and get a favorable reputation from customers, because of their stable performance. We have worked on the development of the cassette type FDG synthesizer (F200) as a system that can be accepted even at those ordinary hospitals and provides stable performance with simple operation and short synthesis time. The basic specifications and features of this synthesizer are: (1) FDG synthesis yield 60 ±5% (EOS), (2) radiochemical purity 95% or higher, (3) FDG synthesis time within 30 minutes, (4) synthesis preparation time within 15 minutes, (5) alkali hydrolysis, (6) a stable yield through pressure control in the reactor, (7) simple preparation based on cassette exchange, (8) reduced operator exposure in two rounds of synthesis through a separation-type refining column shield, and (9) a compact and lightweight design. This report introduces this new FDG synthesizer and describes its actual performance after the delivery.